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. 2023 Jul 6;83(12):1077–1090. doi: 10.1007/s40265-023-01913-5

Table 1.

Incidence of insulin use after the diagnosis of different types of diabetes in national databases

Type of diabetes Setting Insulin use at 1 year Insulin use at 5 years
Incidence Unadjusted odds/hazard ratio Adjusted* odds/hazard ratio Incidence Unadjusted odds/hazard ratio Adjusted* odds/hazard ratio
Type 2 diabetes UK 1.4% 1.0 1.0 4.1% 1.0 1.0
Type 2 diabetes South Korea 10.8% 1.0 1.0 19.3% 1.0 1.0
DEP overall UK 16.3% 13.5 (10.3–17.5) 9.6 (7.0–13.2) 29.6% 9.9 (7.2–13.4) 7.4 (5.2–10.4)
DEP overall South Korea 17.8% 1.71 (1.58–1.85) 1.39 (1.29–1.51) 32.4% 1.63 (1.54–1.73) 1.38 (1.30–1.47)
PPDM-A UK 9.7% 7.5 (5.0–10.9) 6.4 (4.1–9.7) 20.9% 6.2 (4.0–9.3) 5.2 (3.3–8.2)
DEP other than PPDM-A UK 28.9% 28.3 (19.6–40.2) 16.4 (10.4–25.6) 45.8% 19.8 (12.3–31.7) 12.9 (7.4–22.2)

*The UK study adjusted for age, sex, ethnicity, index of multiple deprivation score, smoking status, and BMI. The South Korean study adjusted for age, sex, BMI, fasting plasma glucose, LDL cholesterol, alcohol consumption, smoking status, medical coverage, systolic blood pressure, triglycerides, eGFR, and Charlson comorbidity index

BMI body mass index, eGFR estimated glomerular filtration rate, DEP diabetes of the exocrine pancreas, LDL low-density lipoprotein, PPDM-A, post-pancreatitis diabetes mellitus including diabetes after acute pancreatitis