Table 3.
Case series of three BD patients with the minor G-allele of rs200044200
| BD patient 1 | BD patient 2 | BD patient 3 | |
|---|---|---|---|
| Age (years) | 48 | 58 | 44 |
| Sex | female | male | male |
| Age at onset (years) | 25 | 44 | 35 |
| Duration of illness (years) | 23 | 14 | 9 |
| Family history | SZ (aunt) | Unspecified psychiatric disorder (brother) | ASD/ADHD (son), Dementia (father) |
| Types of BD | I | II | II |
| Developmental disorders | - | - | - |
| Years of education | 14 | 12 | 16 |
| Premorbid IQ | 92 | 110 | 104 |
| Present IQ | 80 | n.a. | n.a. |
| Present occupation | Support for continuous employment type A | Unemployed | Unemployed |
| Former occupation | Children’s nurse | Bus driver | Clerical work |
| Primary symptom | Mania | Depression | Depression |
| Psychotic episode | + | - | - |
| Rapid cycler | + | - | + |
| Present prescription (mg/day) |
Aripiprazole 12 mg, Zotepine 25 mg, Biperiden 2 mg, Clonazepam 2 mg, Loflazepic acid 2 mg, Flunitrazepam 4 mg, Triazolam 0.25 mg, Valproic acid 800 mg |
Flunitrazepam 2 mg, Lithium 400 mg |
Quetiapine 100 mg, Flunitrazepam 2 mg, Zopiclone 7.5 mg, Lithium 900 mg |
BD, bipolar disorder; ASD, autism spectrum disorder; ADHD, attention-deficit hyperactivity disorder