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. 2023 Jul 21;13:11805. doi: 10.1038/s41598-023-38959-0

Table 2.

MIA components and severe periodontitis.

All (N = 254) Periodontally healthy (n = 53) Mild periodontitis (n = 71) Moderate periodontitis (n = 83) Severe periodontitis (n = 47) p-value*
n (%) n (%) n (%) n (%) n (%)
Malnutrition 136 (53.5%) 29 (54.7%) 39 (54.9%) 36 (43.4%) 32 (68.1%) 0.057
Inflammation 81 (31.9%) 14 (26.4%) 20 (28.3%) 22 (26.5%) 25 (53.2%) 0.007
Atherosclerosis 62 (24.4%) 11 (20.8%) 21 (29.6%) 18 (21.7%) 12 (25.5%) 0.62
Numbers of MIA component(s)
 0 66 (26.0%) 16 (30.2%) 20 (28.2%) 26 (31.3%) 4 (8.5%) 0.082
 1 117 (46.1%) 23 (43.4%) 30 (42.3%) 41 (49.4%) 23 (48.9%)
 2 51 (20.1%) 11 (20.8%) 13 (18.3%) 13 (15.7%) 14 (29.8%)
 3 20 (7.9%) 3 (5.7%) 8 (11.3%) 3 (3.6%) 6 (12.8%)

Number of MIA component(s) was defined as the number of relevant components among three components of MIA syndrome (malnutrition, inflammation, and atherosclerosis).

Malnutrition: Geriatric Nutritional Risk Index < 92.

Inflammation: high sensitivity C-reactive protein > 0.3 mg/dL.

Atherosclerosis: underwent invasive procedures for atherosclerotic diseases or had history of cardiovascular events.

*Fisher's exact test.