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. 2023 Jul 21;6:761. doi: 10.1038/s42003-023-05140-2

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Heatmaps show the total number of significant (a) incoming and (b) outgoing interactions for each cell type across different conditions. The expression folds change of (c) ligands and (d) receptors relative to the TN (30 °C, 7 days) group. The color indicates the log2 fold change of gene expression between two conditions. The solid dots indicate significant differential expression (p value < 0.05) and the circle dots indicate non-significance.