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. 2023 Jul 21;6:761. doi: 10.1038/s42003-023-05140-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Dot plot showing the number of significant interactions between each pair of cell types in BAT-SVF of mice housed at TN, RT, and cold (2 and 7 days). The size and color of the circle both represent the number and probability of interactions, respectively. b The proportion of communications in Cell–Cell contact, ECM-Receptor, and Secreted Signaling categories among the predicted communications. c Dot plot presenting the most significant ligand-receptor interaction pairs between adipogenic and immune cells in BAT. The color of the circle represents communication probability. d Heat map showing the communication scores for each ligand–receptor interaction in the cell type pairs across different conditions.