Table 2.
Summary of the most relevant parameters used for simulations of the BM mesoscopic model.
Spatial and time domain parameters | ||
Time step length (Δt) | 4 | hours |
Number of voxels per dimension | 80 | |
Voxel size | 1 | mm |
Voxel volume | 1 | mm3 |
Carrying capacity (K) | 2 ⋅ 105 | mm3 |
Initial and final conditions for simulation | ||
Initial cell number | 10 | |
Limit volume of virtual BM | 10 | cm3 |
Characteristic rates of each cellular process | ||
Division rate | 0.36 | days−1 |
Death rate | 0.144 | days−1 |
Migration speed | 2.88 | mm2 days−1 |
Advantage coefficients | ||
Advantage in division (vdiv) | 1.11-5 | a.d. |
Advantage in migration (vmig) | 1.05-5 | a.d. |