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. 2023 Jul 21;14:4401. doi: 10.1038/s41467-023-40125-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A Heatmap of the agreement between compartments in 1-to-1 orthologs of common proteins in (i) T. brucei BSF and T. congolense BSF, and (ii) T. brucei PCF and T. congolense PCF. Tile colour is scaled by the agreement between life-stages. B Abundance distribution profile for CDA in (i) T. brucei BSF, (ii) T. brucei PCF, (iii) T. congolense BSF and (iv) T. congolense PCF relating allocation to either mitochondrion in T. brucei or cytosol in T. congolense. C Violin plot showing distribution of localisation probabilities across each subcellular compartment according to TAGM-MCMC analysis in T. brucei PCF for CDA. D Proportional representation of compartments in diverse gene set proteins visualised on bar-plots for indicated cell-type. E Lollipop chart showing the fold enrichment for over-represented compartments in diverse gene set proteins for indicated cell-type. Circle size is scaled by count of proteins in indicated compartment and colour by p-value for the over-representation of compartment versus the background proteome. Enrichment analysis was performed using clusterProfiler (v4.0.5) ‘enricher’ function with default settings (hypergeometric test p < 0.05 with Benjamini and Hochberg adjustment).