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. 2023 Jul 21;6:767. doi: 10.1038/s42003-023-05142-0

Fig. 4. N-terminal Htt binds to SERF1a.

Fig. 4

a Primary sequence of the designed Htt peptides. Point mutations of a/d positions in the heptads were highlighted in yellow. b Far-UV CD spectra of Htt peptides. c ITC data of Htt peptides with SERF1a. SERF1a interacts strongly with Htt-3 and NT17. d SAXS data and the extracted Rg values of NT17, SERF1a, and the mixture in 2:1 molar ratio. Data for the mixture were fitted using a DAMMIN model. e SAXS data and Rg values of Htt-3, SERF1a, and the mixture in 2:1 molar ratio. Data for the mixture were fitted using a DAMMIN model.