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Long-term effects of diet on UC induction and Bin1 immunotherapy. Mice on different diets for 7 months were induced UC using 3% DSS. After 6 days, they were treated with Bin1 mAb. Mice on a high fat/high protein diet succumbed to UC. (A) Weight of mice, (B) Length of colon, (C) Normalized colon length. (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 as determined by t test). All results are expressed as Mean ± SD; (n = 5 mice per treatment).
