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. 2023 Jul 21;13:11795. doi: 10.1038/s41598-023-38596-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The effect of NVS-ZP7-4 on growth-inhibiting activity in HCCLM3, Huh7 cells and mouse primary hepatocytes. (A) The chemical structure of NVS-ZP7-4. Huh7 cells (B) were treated with NVS-ZP7-4 (0, 0.0625, 0.125, 0.25, 0.5, 1 μM), OD value was assayed by CCK-8. HCCLM3 (C) Huh7 cells (D) and mouse primary hepatocytes (E) were treated with NVS-ZP7-4 (0, 0.5, 1 μM) for 24 h. ns = no significance, **p < 0.01, ***p < 0.001 versus Control.