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. 2023 Jul 21;13:11775. doi: 10.1038/s41598-023-38881-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Patient-level classification model results using HDSCA3.0 liquid biopsy data. (A) Confusion matrix of predicting NDs and SCLC patients. (B) Feature importance ranking of the top influential clusters. Depicts the relative contribution of each event cluster to making correction predictions. (C) Box plots showing the distribution of the top 20 influential clusters separated by each classification. The plot is shown on a logarithmic scale depicting cells per million (Cell per M).