Table 5.

Genera with the most contribution on model predictions according to SHAP analysis for each cancer type (in descending order of contribution). Corresponding SHAP scores are provided for each feature.

	Overall		Correct predictions		Incorrect predictions
COAD	Porphyromonas	(0.099)	Porphyromonas	(0.216)	Porphyromonas	(2.005)
	Granulicatella	(0.031)	Akkermansia	(0.033)	Akkermansia	(0.289)
	Bacteroides	(0.025)	Granulicatella	(0.031)	Barnesiella	(0.202)
	Solobacterium	(0.021)	Streptococcus	(0.029)	Parabacteroides	(0.115)
	Fusobacterium	(0.020)	Alistipes	(0.024)	Ruminococcus	(0.072)
READ	Porphyromonas	(0.294)	Porphyromonas	(0.965)	Porphyromonas	(0.209)
	Granulicatella	(0.117)	Granulicatella	(0.293)	Parvimonas	(0.156)
	Streptococcus	(0.070)	Streptococcus	(0.139)	Bacteroides	(0.035)
	Solobacterium	(0.042)	Solobacterium	(0.131)	Akkermansia	(0.022)
	Parabacteroides	(0.031)	Campylobacter	(0.111)	Sutterella	(0.022)
HNSC	Helicobacter	(0.236)	Helicobacter	(0.230)	Leptotrichia	(0.020)
	Lactobacillus	(0.044)	Lactobacillus	(0.040)	Alloprevotella	(0.011)
	Fusobacterium	(0.011)	Fusobacterium	(0.013)	Acinetobacter	(0.009)
	Leptotrichia	(0.006)	Alloprevotella	(0.005)	Prevotella	(0.008)
	Alloprevotella	(0.005)	Clostridium	(0.005)	Abiotrophia	(0.008)
STAD	Helicobacter	(0.336)	Helicobacter	(0.433)	Helicobacter	(0.072)
	Lactobacillus	(0.042)	Capnocytophaga	(0.019)	Prevotella	(0.020)
	Veillonella	(0.017)	Lactobacillus	(0.013)	Clostridium	(0.013)
	Fusobacterium	(0.012)	Clostridium	(0.009)	Capnocytophaga	(0.012)
	Prevotella	(0.012)	Fusobacterium	(0.009)	Actinomyces	(0.009)
ESCA	Helicobacter	(0.131)	Helicobacter	(0.203)	Lactobacillus	(0.066)
	Streptococcus	(0.042)	Lactobacillus	(0.097)	Streptococcus	(0.055)
	Prevotella	(0.031)	Acinetobacter	(0.034)	Prevotella	(0.038)
	Lactobacillus	(0.030)	Capnocytophaga	(0.018)	Atopobium	(0.026)
	Aloprevotella	(0.022)	Prevotella	(0.009)	Abiotrophia	(0.011)