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. 2023 Jul 21;14:4419. doi: 10.1038/s41467-023-40070-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Per gene (x axis, all panels) statistics from guQTL analysis (ANOVA and linear regression) in the IgM repertoire, including: a the number of associated variants (P < 9e−6 threshold after Bonferroni correction); b the (i) −log10(P value) of the lead guQTL, (ii) adjusted R² for variance in gene usage explained by the lead guQTL and (iii) the variant type for the lead guQTL; and c the fold change in gene usage between genotypes at the lead guQTL. Summary statistics are provided in Supplementary Data 4.