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. 2023 Jul 7;9(7):e17891. doi: 10.1016/j.heliyon.2023.e17891

Fig. 3.

Fig. 3

The ultrastructural pathological observation of the liver from SD rats. (A) No significant pathological changes were detected in the hepatocyte in the control group. (B) In the TG189 mg/kg group, the reduction or absence of cristae in mitochondria and swollen mitochondria were observed (→). (C&D) In the cytoplasm, increased lipid droplets (☆) and myelin sheath-like structures (→) were observed in the TG189 mg/kg group. (E) In the TG472.5 mg/kg group, the reduction or absence of cristae in mitochondria and swollen mitochondria were observed (→). (F&G) In the cytoplasm, increased lipid droplets (☆) and myelin sheath-like structures (→) were observed in the TG472.5 mg/kg group. (H&I) Enriched mitochondrial cristae and disappeared lipid droplets were observed in the TG189 mg/kg + GA20.25 mg/kg group. (J&K) In the TG472.5 mg/kg + GA20.25 mg/kg group, the lipid droplets in the cytoplasm disappeared, with only occasional evidence of increased electron density in the mitochondria (→). Mt: mitochondrion; N: nucleus.