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. 2023 Jun 21;15(6):e40768. doi: 10.7759/cureus.40768

Table 1. Determination of MIC of cinnamon essential oil, Cajeput essential oil, and their combination, and 0.2% CHX hydrochloride tested against Staphylococcus aureus, Enterococcus faecalis, and Candida albicans.

The results are shown as average values of triplicates in mg/mL (mean ± standard deviation).

The statistical test applied was the Kruskal-Wallis test.

Bonferroni post hoc test was applied.

aGold standard of 0.2% CHX is not statistically significant.

b,cSignificant difference found when compared to 0.2% CHX (in the same row).

*P ≤ 0.05 was considered statistically significant.

MIC, minimum inhibitory concentration; CHX, chlorhexidine hydrochloride solution

Test microorganisms MIC (mg/mL) Statistics
0.2% CHX Cinnamon oil Cajeput oil Combination Z-value P-value
  Staphylococcus aureus   6.51 ± 2.26a 0.33 ± 0.14b 5.21 ± 2.26a 0.57 ± 0.37c 9.039 0.029*
  Enterococcus faecalis   15.63 ± 0.02a 0.41 ± 0.14b 2.12 ± 1.71a 0.49 ± 0.42c 8.484 0.037*
  Candida albicans 10.42 ± 4.51a 1.46 ± 2.11a 1.95 ± 0.01a  3.26 ± 3.95b  6.297  0.098