Figure 3.
Low‐entropy hydration layer regions on the surfaces of ACE2 and RBD. a) ACE2. b) Distribution of low‐entropy hydration layer regions on the surface of ACE2. c–e) The three large low‐entropy regions of the hydration layer. f) The RBD. g) Distribution of low‐entropy hydration layer regions on the surface of the RBD. h–j) The three large low‐entropy regions of the hydration layer. k) RBD‐ACE2 complex. l) Distribution of the low‐entropy hydration layer region on the surfaces of the complex. m,n) The distribution of the low‐entropy hydration layer region on the binding sites of the complex.