Figure 3.
Example dynamics of virtual patient data: We present the dynamics of neutrophils (blue dots, left y-axis) of a specific patient with iiv parameters γ = 0.164, and Emax = 1.422 under (a) therapy scenario 2 and (b) therapy scenario 4. The horizontal line corresponds to 28d according to the assumed memory of the model. Dynamics of scenario-specific cytotoxic drug action Edrug (light blue curves, right y-axis) is also displayed.