Fig. 1.

Study Design. (A) Saliva and plasma samples were collected from healthy and coronavirus disease (COVID-19) donors during the convalescent phase to investigate the viral-host axis in health versus disease. (B) The serology coupled with the global shotgun proteomic analysis of plasma and saliva samples was conducted in parallel, followed by correlation analyses to demographic factors, antibody-, and proteomic responses. (C) This study was designed to capture the inflammatory response (yellow/red dots) during the start of the convalescent phase (>20 days) after clinical symptom; antibody drawings) and investigate the correlation between biological, and demographic factors. Ultimately, our findings will be applied to discover early detection markers for the post-acute sequelae of SARS-CoV-2 infection. Total samples = 110 samples (Healthy Saliva = 13, Healthy Plasma n = 13, COVID19 Saliva n = 42, COVID19 Plasma = 42).