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. 2023 May 8;7(14):3506–3515. doi: 10.1182/bloodadvances.2022009000

Table 3.

Characteristics of participants in the vulnerability subgroup

Reason vulnerable Vulnerability subgroup
MDS (N = 84) MDS/MPN (N = 18) ICUS (N = 12) AML<30% (N = 5) At-risk (N = 30) Total (N = 149)
Age
 ≥75, n (%) 53 (63%) 15 (83%) 6 (50%) 2 (40%) 20 (67%) 96 (64%)
 75-84, n (%) 29 (35%) 11 (61%) 3 (25%) 1 (20%) 13 (43%) 57 (38%)
 ≥85, n (%) 24 (29%) 4 (22%) 3 (25%) 1 (20%) 7 (23%) 39 (26%)
General health
 Health rating of poor or fair, n (%) 55 (65%) 8 (44%) 8 (67%) 4 (80%) 15 (50%) 90 (60%)
Average difficulty with physical activities
 Any activity, n (%) 74 (88%) 18 (100%) 10 (83%) 5 (100%) 27 (90%) 134 (90%)
 Walking quarter-mile, n (%) 62 (74%) 15 (83%) 6 (50%) 5 (100%) 21 (70%) 109 (73%)
 Heavy housework, n (%) 57 (68%) 15 (83%) 8 (67%) 5 (100%) 21 (70%) 106 (71%)
 Stooping, crouching, kneeling, n (%) 49 (58%) 13 (72%) 4 (33%) 4 (80%) 19 (63%) 89 (60%)
 Lifting objects 10 lbs or more, n (%) 28 (33%) 3 (17%) 4 (33%) 3 (60%) 11 (37%) 49 (33%)
 Reaching or extending arms above shoulder, n (%) 21 (25%) 0 (0%) 4 (33%) 2 (40%) 8 (27%) 35 (23%)
 Writing or grasping small objects, n (%) 10 (12%) 0 (0%) 0 (0%) 2 (40%) 4 (13%) 16 (11%)
 Walking across room, n (%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
 Doing light housework, n (%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
Difficulty/require assistance with activities because of health
 Any activity, n (%) 35 (42%) 6 (33%) 5 (42%) 2 (40%) 15 (50%) 63 (42%)
 Shopping, n (%) 28 (33%) 3 (17%) 4 (33%) 2 (40%) 13 (43%) 50 (34%)
 Managing money, n (%) 13 (15%) 4 (22%) 4 (33%) 0 (0%) 5 (17%) 26 (17%)
 Bathing or showering, n (%) 15 (18%) 2 (11%) 0 (0%) 0 (0%) 5 (17%) 22 (15%)

Bold values indicate frequencies and percent vulnerable within a VES-13 domain. The same participant may meet several characteristics. Therefore, the number of participants meeting an individual characteristic within a domain may not sum to total the number of participants who meet any characteristic for the given domain.

N, number of participants in each disease group with an observed QOL score and who are vulnerable based on whether VES-13 ≥3.