Figure 2.

Col12a1 KO mice develop patellar subluxation

(A) Images representing anterior-posterior views of 3-month-old WT and Col12a1 KO mouse hindlimb knee joints after skin removal.

(B) Representative μCT images from 1-month-old WT and KO mouse hindlimb knee joints (n = 4 samples per group, see also Figure S2F). Scale bar: 1 mm.

(C) In plane-matched paraffin sections from WT and Col12a1 KO mice were stained with hematoxylin (nuclei, purple), eosin (cytoplasm, pink) and Alcian blue (proteoglycans, blue). Arrows indicate patella location. Scale bar: 500 μm.

(D) Quantification of patellar subluxation rate in Col12a1 KO mice of different ages. Percentages are given.