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. 2023 Jun 28;26(7):107193. doi: 10.1016/j.isci.2023.107193

Figure 2.

Figure 2

Individuals carrying KCTD19 variants display meiotic metaphase I arrest

(A) Histological analyses of testicular tissues by H&E staining. Black boxes are magnified views of metaphase cells. Green arrowheads indicate spermatogonia, blue arrowheads indicate spermatocytes, red arrowheads indicate spermatids, gray arrowheads indicate Sertoli cells. Scale bars indicate 20 μm.

(B) Immunofluorescence staining of testicular sections from the control and P2034 with PNA (red) and an antibody against H3S10p (green), a marker for nuclei at division. The nuclei were stained with Hoechst 33342 (blue). The insets show magnified images of the field in white rectangles. Scale bars indicate 20 μm.