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. 2023 Jul 8;9(7):e18128. doi: 10.1016/j.heliyon.2023.e18128

Fig. 4.

Fig. 4

GPD1 overexpression activated PI3K/AKT signaling pathway. (A–B) The protein expression levels of PI3K, p-AKT, AKT, p-GSK3β, GSK3β, PTEN, and GAPDH after GPD1 overexpression. (C-D) The protein expression levels of PI3K, AKT, p-AKT, p-GSK3β, GSK3β, and GAPDH after transfection LY294002 inhibitor. (E) The ability of cell proliferation after transfection LY294002 inhibitor. Densitometric analyses of the band intensity ratios for GPD1/GAPDH, PI3K/GAPDH, PTEN/GAPDH, p-AKT/AKT, and p-GSK3β/GSK3β. Data are shown as the mean ± SD (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001).