Figure 2.

BiFCPL exhibits higher efficiency and accuracy than alternative approaches

(A) UpSet plotting of the comparison of the MERC proteome identified by BiFCPL over proteomes identified by split-TurboID and contact-ID. The dot represented presence in the indicated proteome list and a line through the dots represented presence in the related proteome lists. See also Figures S2 and S3 and Table S1.

(B) A clustering analysis for biological processes of MERC proteins analyzed by WebGestalt. The length of the bar is correlated with the enrichment ratio of the indicated item.

(C) An interacting network between proteins located on the mitochondrial outer membrane and ER membrane. The yellow, blue, and red lines represent the interactions within ERM (ER membrane) proteins, interactions between ERM and MOM (mitochondria outer membrane) proteins, and interactions within MOM proteins, respectively. The circle indicates the value of log₂(fold change).