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Effect of P85 (n = 7) and TQD (n = 5) on brain PHT distribution after a bolus dose of drugs in model rats. P85 decreased the AUC ratio up to 33.3% relative to PHT treatment (p < 0.05), while TQD increased the AUC ratio up to almost 47.6% relative to PHT treatment (p < 0.05).
