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. 2023 Feb 18;31(7):1994–2004. doi: 10.1016/j.ymthe.2023.02.014

Figure 2.

Figure 2

Comparison of serum ALT and GAA with γ-interferon ELISPOT assay for anti-AAV8 T cell responses

ELISPOTs were uniformly collected through week 38, and thereafter were not obtained for subject 003 due to inability to travel related to the COVID19 pandemic. Each graph summarizes data for one subject: 001 (A), 002 (B), and 003 (C). The left y axis shows the ELISPOT in spot forming units (SFU), whereas the right y axis shows the scale for GAA (μmol/min/mL) and ALT (units/mL). The x axis shows study days corresponding to the data shown.