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Anti-AAV9 mAbs neutralize functional transduction
Anti-AAV9 reactivity of twenty-one mAbs recovered from three treated infants were serially diluted and tested for anti-AAV9 reactivity by ELISA (top panel) or AAV9 transduction neutralization assay (bottom panel). Data are pooled from duplicate and triplicate independent experiments for the ELISA and neutralization assays, respectively. Error bars indicate SEM.
