Table 2.
Binding kinetics of the Fabs (average of n = 3 experiments)
Fab | kD, nM | Fab | kD, nM | Fab | kD, nM |
---|---|---|---|---|---|
1-1 | 0.30 | 2-1 | 0.22 | 3-1 | 0.24 |
1-2 | 0.23 | 2-2 | 1.29 | 3-2 | 0.18 |
1-3 | 0.28 | 2-3 | 24.80 | 3-3 | 0.05 |
1-4 | 2.30 | 2-4 | 2.57 | 3-4 | 6.12 |
1-5 | 0.15 | 2-5 | 0.26 | 3-5 | 26.40 |
1-6 | 0.25 | 2-6 | 2.94 | 3-6 | 0.18 |
1-7 | 199.50 | 2-7 | 14.46 | 3-7 | 30.60 |
ADK9 | 0.21 | HL2368 | 1.87 | HL2372 | 0.29 |