Figure 6.

Vision testing. Scotopic vision of CNGB1 mutant dogs restored by gene augmentation therapy

Vision testing outcome from four-choice vision testing device showing results under scotopic lighting levels (0.057 lux). (A) Shows mean (+/−SEM) percentage correct exit choices. (B) Mean (+/− SEM) time to exit. While the control dogs (GP0) fail to regularly choose the open exit and take a prolonged time to exit the device, dogs in all treated groups were able to identify the open exit accurately and rapidly exit the device. Gp1 dogs and two of the Gp2 dogs were only kept for 6 months so are not shown in the 12-month post-injection graphs.