Figure 2.
Focal HFRT induces systemic alterations in MDSCs
Representative flow plots of MDSCs in the blood (A), spleen (B), or bone marrow (C) of mice bearing CT26, 4T1 or MC38 tumors on day 7 after radiation initiation (gated on live cells). Bar plots showing fractions of MDSCs in the blood, spleen, or bone marrow of mice. Results are presented as mean ± SEM. ∗p < 0.05 and ∗∗p < 0.01; NS, p > 0.05 (unpaired Student’s t test). (D) Line chart of the proportion of MDSCs in different tissues of mice.