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. 2023 May 13;31(7):1960–1978. doi: 10.1016/j.ymthe.2023.05.007

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© 2023 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Overview of histological subtypes of all lung cancers and mutation profile of major subtypes of NSCLC

(A) Histological subtypes of all lung cancers.³^,⁵^,⁶^,⁷^,⁸^,⁹^,¹⁰^,¹¹ Since the proportion of LCC in all lung cancers is not available, we estimated that LCC accounts for 2.7% of all lung cancers based on its fraction in NSCLC. LASC, lung adenosquamous carcinoma; LCC, large cell carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; NSCLC, non-small cell lung cancer; pLEC, pulmonary lymphoepithelial carcinoma; pNMC, pulmonary nuclear protein of the testis midline carcinoma; PSC, pulmonary sarcomatoid carcinoma; pSGT, pulmonary salivary gland-type tumors; SCLC, small cell lung cancer.

(B) The frequency of driver mutations in LUAD and LUSC. Data were collected from the LUNGevity Foundation (https://www.lungevity.org/).