Table 4.

PDX models for rare lung cancers

Publication	Tissue collect	Mouse strain	Engraftment rate	Rare lung cancer (n)
Fichtner et al.177	surgical resection	NOD/SCID	24.5%a	PSC (4), LCC (1)
Wang et al.172	surgical resection	NOD/SCID	28.8%a	LASC (1), PSC (5)
John et al.178	surgical resection	NOD/SCID	PSC 100% (1/1); LCC 60% (3/5)	PSC (1), LCC (3)
Sun et al.173	biopsy, surgical resection	NOD/SCID	NA	LASC (1), PSC (2), LCC (1)
Woo et al.171	biopsy, pleural effusion, surgical resection	NSG	38.0%a	LASC (2), PSC (1)
Kita et al.181	surgical resection	NSG, SHO	LCC 50% (1/2)	LCC (1)
Fang et al.174	surgical resection	BALB/c nude	NA	LASC (3), PSC (2), LCC (2)
Nakajima et al.182	EBUS-guided biopsy	NSG	LCC 100% (1/1)	LCC (1)

NOD, non-obese diabetic; NSG, NOD-SCID gamma; SCID, severely compromised immune deficient; SHO, SCID Hairless Outbred; NA, not available.

^aTotal engraftment rate.