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. 2023 Jul 21;6(7):e2322515. doi: 10.1001/jamanetworkopen.2023.22515

Table 2. Oncology Trial Participation by Cancer Type and Race and Ethnicity.

Cancer type race and ethnicity Clinical trial participation
No. of patients/total No. in group (%) Adjusted hazard ratio (95% CI)a
Advanced non–small cell lung cancer
Black 97/2496 (3.9) 0.45 (0.37-0.56)
Latinx 58/993 (5.8) 0.74 (0.57-0.96)
White 1303/17 472 (7.5) 1 [Reference]
Metastatic breast cancer
Black 65/1503 (4.3) 0.67 (0.52-0.87)
Latinx 34/1047 (3.2) 0.45 (0.32-0.64)
White 464/7362 (6.3) 1 [Reference]
Metastatic colorectal cancer
Black 75/1488 (5.0) 0.74 (0.58-0.94)
Latinx 43/1222 (3.5) 0.46 (0.34-0.63)
White 537/7886 (6.8) 1 [Reference]
Multiple myeloma
Black 45/938 (4.8) 0.69 (0.50-0.95)
Latinx 15/379 (4.0) 0.61 (0.37-1.00)
White 184/3031 (6.1) 1 [Reference]
Metastatic pancreatic cancer
Black 25/487 (5.1) 0.54 (0.36-0.81)
Latinx 16/332 (4.8) 0.46 (0.27-0.77)
White 370/3775 (9.8) 1 [Reference]
Overall
Black 307/6912 (4.4) 0.57 (0.51-0.65)
Latinx 166/3973 (4.2) 0.54 (0.46-0.63)
White 2858/39 526 (7.2) 1 [Reference]
a

Models were adjusted for clinical characteristics (age [continuous], gender, Eastern Cooperative Oncology Group performance status, year of diagnosis), as appropriate, with White race as the reference. Racial and ethnic groups were mutually exclusive. Separate models were estimated by cancer using a stratified approach.