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. 2023 Jun 15;18(7):1451–1467. doi: 10.1016/j.stemcr.2023.05.012

Figure 1.

Figure 1

Ala-Gln supplementation alleviates early weaning-induced growth retardation and intestinal morphology damage

(A) Experimental procedure.

(B–D) The average weight of suckling and post-weaning mice was monitored during the experiment (n = 5–8 mice, means ± SEM; ∗p < 0.05, ∗∗p < 0.01; t test, results of 3–4 independent experiments).

(E and F) The average daily body weight gain (E), initial weight, and final weight (F) were measured during the experiment (n = 7 to 20 mice, means ± SEM; ∗p < 0.05, ∗∗p < 0.01; one-way ANOVA, results of 3 independent experiments).

(G and H) The small intestinal length (G) and small intestinal mass (H) were determined (n = 6–7 mice, means ± SEM; ∗p < 0.05, ∗∗p < 0.01; one-way ANOVA, results of 3 independent experiments).

(I) Representative images of H&E staining of jejunum in mice on day 7 post-weaning are shown. Scale bars, 100 μm.

(J and K) The villous height (J) and crypt depth (K) in mice were measured on day 7 post-weaning (n = 8 mice, means ± SEM; ∗p < 0.05, ∗∗p < 0.01; one-way ANOVA, results of 3 independent experiments).