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The mechanisms by which m6A modification regulates DCs
METTL3 positively regulates the function of dendritic cells (DCs) by increasing CD40, CD80, and Tirap (TLR4 signaling adaptor) translation. YTHDF1 inhibits the cross-priming ability of DCs targeting lysosomal proteases, suppressing the CD8+ T cell antitumor response.
