Table 2.

Response rates in the efficacy-evaluable population

Response rates	Efficacy-evaluable population (n = 147)
CR∗or CRh
n (%) [95% CI]	51 (35) [27.0-43.0]
Median time to CR/CRh, mo (range)	1.9 (0.9-5.6)
CR∗
n (%) [95% CI]	47 (32) [24.5-40.2]
Median time to CR, months (range)	2.8 (0.9-7.4)
Overall response
N (%) [95% CI]	71 (48) [40.0-56.7]
Median time to first overall response, mo (range)	1.9 (0.9-10.2)
Best overall response, n (%)
CR∗	47 (32)
CRh	4 (3)
CRi	15 (10)
PR	3 (2)
MLFS	2 (1)
SD†	42 (29)
Progressive disease	10 (7)
Not evaluable/not done	6 (4) / 18 (12)

CRi, CR with incomplete blood count recovery; PR, partial remission; SD, stable disease (failure to achieve at least a PR but not meeting criteria for progressive disease. SD for a period of ≥8 weeks indicates clinical benefit).

^∗Includes patients with CR, complete cytogenetic remission, and complete molecular remission.

^†Includes 3 patients considered to have clinical benefit by the treating physician and 2 patients considered to have resistant but stable disease.