Table 4.

Patients with treatment-emergent hepatic AESI (greater than 1%) of all grades, and of grade 3 or 4 severity

Patients with hepatic AESI (>1%)	All grades, n (%)	Grade 3 or 4, n (%)
Patients with at least 1 treatment-emergent hepatic AESI	38 (25)	23 (15)
Investigations	33 (22)	19 (12)
Alanine aminotransferase increased	18 (12)	7 (5)
Aspartate aminotransferase increased	14 (9)	4 (3)
Gamma-glutamyltransferase increased	10 (7)	8 (5)
Blood bilirubin increased	8 (5)	2 (1)
Hepatic enzyme increased	7 (5)	5 (3)
Liver function test deviated	3 (2)	3 (2)