Table 1.
Baseline characteristics of patients with PV vs HCs
| Characteristics | Group |
P value | |
|---|---|---|---|
| PV | HCs | ||
| Patients, N | 102 | 42 | |
| Sex | |||
| Female, n (%) | 45 (44.1) | 17 (40.5) | .72 |
| Age, y | |||
| Median (range) | 70 (31-85) | 71 (66-74) | .083∗ |
| Body mass index, kg/m2 | |||
| Mean (SD) | 26.0 (3.9) | 24.9 (2.4) | .34† |
| Smoking | |||
| Current smoker, n (%) | 8 (7.8) | 1 (2.4) | .28 |
| Former smoker, n (%) | 43 (42.2) | 13 (31) | .35 |
| Never smoker, n (%) | 50 (49) | 26 (61.9) | .28 |
| Unknown, n (%) | 1 (1) | 2 (4.8) | |
| Hypertension | |||
| Yes, n (%) | 55 (53.9) | 16 (38.1) | .1 |
| No, n (%) | 47 (46.1) | 26 (61.9) | .36 |
| Unknown, n (%) | 0 (0) | 0 (0) | |
| Comorbidity index‡ | |||
| Median (range) | 1 (0-9) | 0 (0-4) | .058∗ |
| n (%) | |||
| No comorbidities (CCI = 0) | 36 (35.3) | 22 (52.4) | .064 |
| Low burden (CCI = 1-2) | 42 (41.2) | 16 (38.1) | .85 |
| Moderate to high (CCI > 2) | 24 (23.5) | 4 (9.5) | .065 |
| Blood test | |||
| Leukocyte, ×109/L | |||
| Median (range) | 5.7 (2.5-21.8) | 6.2 (4.5-9.4) | .15∗ |
| Hematocrit, % | |||
| Mean (SD) | 42 (4) | 43 (3) | .037† |
| Thrombocyte, ×109/L | |||
| Median (range) | 309 (113-884) | 227 (125-355) | <.001∗ |
| eGFR | |||
| Mean (SD) | 78.2 (16.5) | 73.1 (13.2) | .14† |
CCI, Charlson Comorbidity Index; eGFR, estimated glomerular filtration rate; SD, standard deviation.
∗
Pairwise Wilcoxon rank sum test.
†
Analysis of variance with post hoc Tukey honest significant difference test.
‡
Comorbidity scores were calculated using CCI.