Table 3.
Differences in hemodynamics between responders and non-responders to vasopressin loading
| n | Responder | Non-responder | p value |
|---|---|---|---|
| MAP change > 22 mmHg | MAP change ≤ 22 mmHg | ||
| 62 | 30 | ||
| Pre SBP mm Hg | 107.3 ± 22.2 | 104.8 ± 22.2 | 0.59 |
| Pre DBP mm Hg | 51.0 ± 10.2 | 50.8 ± 11.4 | 0.59 |
| Pre MAP mm Hg | 68.6 ± 11.8 | 69.3 ± 15.1 | 0.84 |
| Pre HR /min | 93.6 ± 22.6 | 98.1 ± 22.6 | 0.38 |
| Pre CO l/min | 4.4 (3.5, 6.3) | 4.2 (3.7, 5.3) | 0.65 |
| Pre SV ml | 49 (40, 58) | 42.5 (34.3, 63.5) | 0.41 |
| Pre SVV % | 17 (13, 22.3) | 12 (7.8, 19.3) | 0.015 |
| Pre dPmx | 856 (658, 1190) | 856 (576, 1284) | 0.87 |
| Pre SVR dynes/s/cm5 | 1162 (844, 1441) | 1190 (845, 1413) | 0.99 |
| Pre CVP mm Hg | 5 (5, 7.5) | 5 (4, 9.3) | 0.85 |
| Post SBP mm Hg | 157.8 ± 25.5 | 126.0 ± 28.2 | < 0.0001 |
| Post DBP mm Hg | 75.3 ± 12.9 | 62.0 ± 14.8 | < 0.0001 |
| Post MAP mm Hg | 105.2 ± 12.5 | 81.5 ± 17.3 | < 0.0001 |
| Post HR/min | 88.6 ± 19.9 | 93.9 ± 22.6 | 0.27 |
| Post CO l/min | 4.6 (3.3, 5.7) | 3.8 (2.8, 5.0) | 0.11 |
| Post SV ml | 52 (42, 68) | 42.5 (32.3, 54.5) | 0.025 |
| Post SVV % | 13 (7.5, 17) | 9.5 (8, 19.5) | 0.94 |
| Post dPmx | 1264 (1035, 1684) | 956 (606.5, 1377) | 0.024 |
| Post SVR dynes/s/cm5 | 1702 (1490, 2348) | 1465 (1082, 1979) | 0.068 |
| Post CVP mm Hg | 9 (5, 10) | 7.5 (5.75, 12) | 0.53 |
Data were expressed as a mean ± standard deviation for normally distributed continuous variables or median (interquartile range) for non-normally distributed continuous variables
MAP mean arterial pressure; SBP systolic blood pressure, DBP diastolic blood pressure; HR heart rate; CO cardiac output; SV stroke volume; SVV stroke volume variation, SVR systemic vascular resistance; CVP central venous pressure