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. 2023 Jul 22;28:247. doi: 10.1186/s40001-023-01193-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Functional analysis of DEGs. A Bubble chart of GO enrichment analysis of differential BM genes in the CD group, and the top 10 functions are listed respectively. B Circle chart of GO enrichment analysis of differential BM genes in CD group and the distribution of top 6 functions are listed respectively. C Bubble chart of differential BM genes KEGG enrichment analysis in CD group and the top 10 functional pathways are listed. D Circle plot of CD group differential BM gene KEGG enrichment analysis. E, F In the CD group analysis, GSEA analysis was performed with the immune-related gene set as a reference, and the top 5 enriched immune gene sets were listed, respectively