Table 3.
Univariable and multivariable regression table for baseline RWT
| Baseline RWT (Log) | Univariable (n = 156) | Multivariable (n = 142) | ||
|---|---|---|---|---|
| β | p | β | p | |
| Demographics | ||||
| Age, per year | 0.0047 | 0.004 | 0.0043 | 0.023 |
| Male versus female | 0.028 | 0.60 | … | … |
| Race | ||||
| White | REF | REF | ||
| Black | 0.056 | 0.35 | … | … |
| Hispanic | 0.010 | 0.83 | ||
| Other | − 0.028 | 0.78 | ||
| BMI, per kg/m2 | 0.0082 | 0.013 | 0.0033 | 0.37 |
| RA characteristics | ||||
| RA duration (square root), per year | 0.0010 | 0.93 | … | … |
| AM stiffness (square root), per minute | − 0.0050 | 0.35 | … | … |
| Joint deformities (square root) | − 0.0076 | 0.63 | … | … |
| CDAI (square root), per unit | 0.016 | 0.20 | … | … |
| DAS28CRP, per unit | 0.0299 | 0.051 | 0.026 | 0.10 |
| RF > 40, units | 0.0062 | 0.88 | … | … |
| CCP > 250, units | − 0.034 | 0.42 | − 0.029 | 0.49 |
| Square root CRP, per mg/L | 0.028 | 0.082 | … | … |
| Log IL-6, per pg/mL | 0.024 | 0.18 | … | … |
| Log BNP, per pg/mL | − 0.00084 | 0.98 | … | … |
| Log troponin-I, per pg/mL | 0.049 | 0.010 | … | … |
| Log galectin-3, per ng/mL | 0.11 | 0.021 | … | … |
| RA medication | ||||
| NSAID use, yes versus no | − 0.051 | 0.22 | … | … |
| Prednisone use, yes versus no | 0.0047 | 0.91 | … | … |
| Leflunomide use, yes versus no | 0.097 | 0.19 | … | … |
| TNF inhibitor use, yes versus no | − 0.070 | 0.12 | … | … |
| Tocilizumab use, yes versus no | 0.27 | 0.12 | 0.50 | 0.043 |
| CV risk factors | ||||
| Current smoker, yes versus no | 0.054 | 0.41 | … | … |
| Ever smoker, yes versus no | 0.091 | 0.028 | 0.057 | 0.19 |
| SBP, mm/Hg | 0.0018 | 0.16 | − 0.00025 | 0.85 |
| Statin use, yes versus no | 0.013 | 0.82 | … | … |
| ASA use, yes versus no | 0.0023 | 0.97 | … | … |
| Total cholesterol, per mg/dl | 0.000042 | 0.94 | … | … |
| LDL, per mg/dl | 0.00042 | 0.52 | … | … |
| Square root HDL, per mg/dl | − 0.022 | 0.21 | − 0.011 | 0.55 |
| Prob > F | 0.0080 | |||
| R2 | 0.14 | |||
| Adjusted R2 | 0.0897 | |||