. 2023 Jul 21;27:72. doi: 10.1186/s40824-023-00385-8

Table 3.

Overview of display technologies

Screening technologies	Display principle	Selection principle	Typical library size
Phage display	Protein/peptide library is displayed on the surface of phage particles	Capture/elution	10^9–10
Cell-surface display	Protein/peptide library is displayed on the surface of a living cell as a fusion to cell surface protein	FACS selection	10⁷ eukaryotes 10^8–10 prokaryote
Ribosome display	Protein/peptide library is displayed on the stalled ribosome/mRNA complex	Capture/elution	10^12–14
mRNA/cDNA display	Protein/peptide library is displayed as covalently attached peptides to its encoding mRNA/cDNA	Capture/elution	10^12–14