Table 2.

Structural and functional changes in the PPR protein upon mutation

start (aa)	end (aa)	feature	details
441	463	TRANSMEM	Helical; Name = 7; (Potential).	lost
464	593	TOPO_DOM	Cytoplasmic (Potential).	might get lost (downstream of altered splice site)
471	471	CONFLICT	K -> N (in Ref.2).	might get lost (downstream of altered splice site)
473	473	CONFLICT	S -> C (in Ref.2).	might get lost (downstream of altered splice site)
474	474	MUTAGEN	W->A: Strongly reduced interaction with G protein subunits GNB1 and GNG2; when associated with A-477.	might get lost (downstream of altered splice site)
474	477	MOTIF	Important for interaction with G proteins.	might get lost (downstream of altered splice site)
477	477	MUTAGEN	W->A: Strongly reduced interaction with G protein subunits GNB1 and GNG2; when associated with A-474.	might get lost (downstream of altered splice site)