Table 1.
Author year | Country | Trial design | Sample | Mean age | Baseline disease | Intervention | Dosage | Duration | Outcomes | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|
T | C | T | C | T | C | mg/d | /w | |||||
Adler, A. J.,1997 [20] | Canada | parallel | 11 | 11 | 45.9 | 45.4 | hyperlipidemia | GT | placebo | 900 | 12 | TG,TC,LDL,HDL |
Aslani, N.,2016 [21] | Iran | parallel | 27 | 28 | 45.3 | 39.3 | hyperlipidemia | RG | none | 8 | BMI,TG,TC,LDL,HDL | |
Auer 1990 [22] | Germany | parallel | 24 | 23 | NR | NR | hypertension | GT | placebo | 600 | 12 | SBP,DBP |
Byrne, DJ.,1999 [23] | UK | parallel | 20 | 11 | NR | NR | hyperlipidemia | GT | placebo | 900 | 24 | TG,TC,LDL,HDL |
Gardner, CD.,2001 [24] | USA | parallel | 16 | 18 | 50.2 | 51.6 | hyperlipidemia | GT | placebo | 999 | 12 | TG,TC,LDL,HDL |
Higashikawa, F., 2012 [25] | Japan | parallel | 28 | 26 | 52 | 51.4 | hyperlipidemia | PG | placebo | 900 | 12 | BMI,TG,TC,LDL,HDL,FBG |
Isaacsohn, JL.,1998 [26] | USA | parallel | 24 | 18 | 58 | 57.4 | hyperlipidemia | GT | placebo | 900 | 12 | BMI,TG,TC,LDL,HDL,SBP,DBP |
Jain, AK.,1993 [27] | USA | parallel | 20 | 22 | 48 | 55 | hyperlipidemia | GT | placebo | 900 | 12 | TG,TC,LDL,HDL,FBG,SBP,DBP |
Jung, ES.,2014 [28] | Korea | parallel | 28 | 27 | 50.13 | 50.83 | hyperlipidemia | AGE | placebo | 12 | TG,TC,LDL,HDL | |
Kannar, D.,2001 [29] | Australia | parallel | 19 | 22 | 52.6 | 57.4 | hyperlipidemia | GT | placebo | 800 | 12 | TG,TC,LDL,HDL |
Nakasone,Yasushi, 2013 [30] | Japan | parallel | 19 | 21 | 58 | 59 | hypertension | GT | placebo | 188 | 12 | SBP,DBP |
Peleg, A.,2003 [31] | Israel | parallel | 13 | 20 | 52.4 | 54.7 | hyperlipidemia | GT | placebo | 16 | TG,TC,LDL,HDL | |
Riad, Karin,2018 [32] | Australia | parallel | 23 | 26 | 62.8 | 61.9 | hypertension | AGE | placebo | 2400 | 12 | WC,BMI,TG,LDL,HDL,FBG,SBP,DBP |
Sangouni, Abbas A,2020 [33] | Iran | parallel | 45 | 43 | 45.2 | 44.2 | NAFLD | GT | placebo | 1600 | 12 | WC,BMI,TG,TC,LDL,HDL |
Sangouni, Abbas A,2021 [14] | Iran | parallel | 42 | 42 | 46.9 | 44.6 | MetS | GT | placebo | 1600 | 12 | TG,TC,LDL,HDL |
Sharifi, F.,2010 [34] | Iran | parallel | 20 | 20 | 47.9 | 50.5 | MetS | GT | placebo | 1800 | 6 | WC,BMI,TG,TC,HDL,FBG,SBP,DBP |
Simons, LA.,1995 [35] | Australia | crossover | 12 | 17 | 53.6 | 53.6 | hyperlipidemia | GT | placebo | 900 | 12 | TG,TC,LDL,HDL,SBP,DBP |
Superko, HR. 2000 [36] | USA | parallel | 25 | 25 | 53 | 53 | hyperlipidemia | GT | placebo | 900 | 12 | SBP,DBP |
Valls, RM.,2022 [37] | Spain | crossover | 32 | 34 | 53.7 | 52.7 | hyperlipidemia | AGE | placebo | 250 | 6 | SBP,DBP |
T Treatment group, C Control group, NR: not reported, NAFLD Non-alcoholic fatty liver disease, MetS Metabolic syndrome, GT Garlic tablet, RG Row garlic, PG Processed garlic, AGE Aged garlic extract, WC Waist circumference, BMI Body mass index, TG Triglycerides, TC Total cholesterol, LDL-c Low-density lipoprotein cholesterol, HDL-c High-density lipoprotein cholesterol, FBG Fasting blood glucose, SBP Systolic blood pressure, DBP Diastolic blood pressure