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. 2023 Jul 22;23:260. doi: 10.1186/s12906-023-04038-0

Table 1.

Basic information of the included randomized controlled trials

Author year Country Trial design Sample Mean age Baseline disease Intervention Dosage Duration Outcomes
T C T C T C mg/d /w
Adler, A. J.,1997 [20] Canada parallel 11 11 45.9 45.4 hyperlipidemia GT placebo 900 12 TG,TC,LDL,HDL
Aslani, N.,2016 [21] Iran parallel 27 28 45.3 39.3 hyperlipidemia RG none 8 BMI,TG,TC,LDL,HDL
Auer 1990 [22] Germany parallel 24 23 NR NR hypertension GT placebo 600 12 SBP,DBP
Byrne, DJ.,1999 [23] UK parallel 20 11 NR NR hyperlipidemia GT placebo 900 24 TG,TC,LDL,HDL
Gardner, CD.,2001 [24] USA parallel 16 18 50.2 51.6 hyperlipidemia GT placebo 999 12 TG,TC,LDL,HDL
Higashikawa, F., 2012 [25] Japan parallel 28 26 52 51.4 hyperlipidemia PG placebo 900 12 BMI,TG,TC,LDL,HDL,FBG
Isaacsohn, JL.,1998 [26] USA parallel 24 18 58 57.4 hyperlipidemia GT placebo 900 12 BMI,TG,TC,LDL,HDL,SBP,DBP
Jain, AK.,1993 [27] USA parallel 20 22 48 55 hyperlipidemia GT placebo 900 12 TG,TC,LDL,HDL,FBG,SBP,DBP
Jung, ES.,2014 [28] Korea parallel 28 27 50.13 50.83 hyperlipidemia AGE placebo 12 TG,TC,LDL,HDL
Kannar, D.,2001 [29] Australia parallel 19 22 52.6 57.4 hyperlipidemia GT placebo 800 12 TG,TC,LDL,HDL
Nakasone,Yasushi, 2013 [30] Japan parallel 19 21 58 59 hypertension GT placebo 188 12 SBP,DBP
Peleg, A.,2003 [31] Israel parallel 13 20 52.4 54.7 hyperlipidemia GT placebo 16 TG,TC,LDL,HDL
Riad, Karin,2018 [32] Australia parallel 23 26 62.8 61.9 hypertension AGE placebo 2400 12 WC,BMI,TG,LDL,HDL,FBG,SBP,DBP
Sangouni, Abbas A,2020 [33] Iran parallel 45 43 45.2 44.2 NAFLD GT placebo 1600 12 WC,BMI,TG,TC,LDL,HDL
Sangouni, Abbas A,2021 [14] Iran parallel 42 42 46.9 44.6 MetS GT placebo 1600 12 TG,TC,LDL,HDL
Sharifi, F.,2010 [34] Iran parallel 20 20 47.9 50.5 MetS GT placebo 1800 6 WC,BMI,TG,TC,HDL,FBG,SBP,DBP
Simons, LA.,1995 [35] Australia crossover 12 17 53.6 53.6 hyperlipidemia GT placebo 900 12 TG,TC,LDL,HDL,SBP,DBP
Superko, HR. 2000 [36] USA parallel 25 25 53 53 hyperlipidemia GT placebo 900 12 SBP,DBP
Valls, RM.,2022 [37] Spain crossover 32 34 53.7 52.7 hyperlipidemia AGE placebo 250 6 SBP,DBP

T Treatment group, C Control group, NR: not reported, NAFLD Non-alcoholic fatty liver disease, MetS Metabolic syndrome, GT Garlic tablet, RG Row garlic, PG Processed garlic, AGE Aged garlic extract, WC Waist circumference, BMI Body mass index, TG Triglycerides, TC Total cholesterol, LDL-c Low-density lipoprotein cholesterol, HDL-c High-density lipoprotein cholesterol, FBG Fasting blood glucose, SBP Systolic blood pressure, DBP Diastolic blood pressure