Table 1.
Gut Microbiome Results of the PD and the Control Groups
| Gut microbiome | Cases (n = 30) |
Control (n = 35) |
Test of Sig. | p |
|---|---|---|---|---|
| Bacteroides | ||||
| Min. – Max. | 5.78E-03–9.47E-01 | 2.25E-03–9.08E-01 |
U= 355.500 |
0.026 * |
| Mean ± SD. | 2.76E-01 ± 2.61E-01 | 1.48E-01 ± 1.89E-01 | ||
| Median | 1.89E-01 | 8.18E-02 | ||
| IQR | 5.00E-02–4.83E-01 | 3.16E-02–1.76E-01 | ||
| Prevotella | ||||
| Min. – Max. | 4.33E-06–7.61E-01 | 1.14E-05–9.00E-01 |
U = 463.0 |
0.415 |
| Mean ± SD. | 1.92E-01 ± 2.60E-01 | 1.77E-01 ± 2.42E-01 | ||
| Median | 2.69E-02 | 6.95E-02 | ||
| IQR | 4.30E-04–4.27E-01 | 5.17E-03–2.44E-01 | ||
| Ruminococcus | ||||
| Min. – Max. | 1.39E-04–3.19E-01 | 1.87E-04–6.34E-01 |
U = 394.500 |
0.086 |
| Mean ± SD. | 4.78E-02 ± 7.24E-02 | 7.70E-02 ± 1.14E-01 | ||
| Median | 2.41E-02 | 4.82E-02 | ||
| IQR | 6.75E-03–4.67E-02 | 1.99E-02–8.55E-02 | ||
| Firmicutes | ||||
| Min. – Max. | 3.24E-06–9.52E-01 | 1.67E-01–9.47E-01 |
t = 3.331* |
0.001 * |
| Mean ± SD. | 3.45E-01 ± 2.25E-01 | 5.27E-01 ± 2.15E-01 | ||
| Median | 3.13E-01 | 5.00E-01 | ||
| IQR | 1.82E-01–4.77E-01 | 4.07E-01–6.84E-01 | ||
| Bacteroidetes | ||||
| Min. – Max. | 1.72E-02–8.16E-01 | 4.17E-02–8.65E-01 |
t = 0.487 |
0.628 |
| Mean ± SD. | 4.44E-01 ± 2.06E-01 | 4.19E-01 ± 2.05E-01 | ||
| Median | 4.44E-01 | 3.77E-01 | ||
| IQR | 3.27E-01–5.95E-01 | 2.86E-01–5.75E-01 | ||
| Lactobacilli | ||||
| Min. – Max. | 1.97E-05–5.91E-02 | 1.55E-05–3.15E-01 |
U = 424.0 |
0.184 |
| Mean ± SD. | 9.13E-03 ± 1.30E-02 | 1.61E-02 ± 5.37E-02 | ||
| Median | 5.26E-03 | 9.28E-04 | ||
| IQR | 7.81E-04–1.22E-02 | 2.50E-04–8.90E-03 | ||
| Bifidobacteria | ||||
| Min. – Max. | 8.76E-06–4.90E-02 | 2.03E-05–1.47E-01 |
U = 279.0* |
0.001 * |
| Mean ± SD. | 8.77E-03 ± 1.26E-02 | 2.69E-02 ± 3.04E-02 | ||
| Median | 1.86E-03 | 2.06E-02 | ||
| IQR | 3.63E-04–1.25E-02 | 4.74E-03–3.42E-02 | ||
| P/B Ratio | ||||
| Min. – Max. | 0.0–88.58 | 0.0–95.97 |
U = 406.0 |
0.117 |
| Mean ± SD. | 6.24 ± 16.77 | 8.40 ± 18.78 | ||
| Median | 0.08 | 0.65 | ||
| IQR | 0.0–4.13 | 0.06–5.24 | ||
| F/B ratio | ||||
| Min. – Max. | 0.0–5.65 | 0.30–17.12 |
U = 298.0* |
0.003 * |
| Mean ± SD. | 1.04 ± 1.16 | 1.95 ± 2.81 | ||
| Median | 0.62 | 1.32 | ||
| IQR | 0.34–1.39 | 0.86–1.91 |
t: Student t-test U: Mann Whitney test.
p: p value for association between different categories.
*: Statistically significant at p ≤ 0.05.