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. 2023 Jul 21;21:266. doi: 10.1186/s12916-023-02940-5

Table 1.

Baseline characteristics of study population according to the quartiles of dietary inflammatory index

Characteristics Overall Dietary inflammatory indexa P valueb
First quartile (n = 41,587) Second quartile (n = 41,607) Third quartile (n = 41,587) Fourth quartile (n = 41,596)
Age (mean ± SD) 55.91 ± 7.98 56.91 ± 7.83 56.20 ± 7.91 55.71 ± 7.95 54.82 ± 8.08  < 0.001
Female sex (%) 88,802 (53.4) 20,653 (49.7) 21,656 (52.0) 22,474 (54.0) 24,019 (57.7)  < 0.001
Ethnic (%)  < 0.001
 White 159,256 (95.7) 39,970 (96.1) 40,324 (96.9) 40,060 (96.3) 38,902 (93.5)
 Asian 2398 (1.4) 489 (1.2) 397 (1.0) 546 (1.3) 966 (2.3)
 Black 2018 (1.2) 457 (1.1) 328 (0.8) 377 (0.9) 856 (2.1)
 Chinese 470 (0.3) 125 (0.3) 94 (0.2) 112 (0.3) 139 (0.3)
 Mixed 1037 (0.6) 249 (0.6) 232 (0.6) 209 (0.5) 347 (0.8)
 Other 1198 (0.7) 297 (0.7) 232 (0.6) 283 (0.7) 386 (0.9)
Education level (%)  < 0.001
 Higher education qualifications/professional qualifications 118,527 (71.2) 30,727 (73.9) 30,822 (74.1) 29,621 (71.2) 27,357 (65.8)
 Others 47,850 (28.8) 10,860 (26.1) 10,785 (25.9) 11,966 (28.8) 14,239 (34.2)
TDI (mean ± SD)  − 1.58 ± 2.86  − 1.68 ± 2.81  − 1.75 ± 2.76  − 1.62 ± 2.84  − 1.27 ± 3.02  < 0.001
Smoking status (%)  < 0.001
 Never 93,931 (56.5) 23,560 (56.7) 23,926 (57.5) 23,408 (56.3) 23,037 (55.4)
 Previous 59,476 (35.7) 15,501 (37.3) 15,008 (36.1) 14,953 (36.0) 14,014 (33.7)
 Current 12,970 (7.8) 2526 (6.1) 2673 (6.4) 3226 (7.8) 4545 (10.9)
Drinking status (%)  < 0.001
 Never 5097 (3.1) 1132 (2.7) 1052 (2.5) 1158 (2.8) 1755 (4.2)
 Previous 4955 (3.0) 1140 (2.7) 1056 (2.5) 1159 (2.8) 1600 (3.8)
 Current 156,325 (94.0) 39,315 (94.5) 39,499 (94.9) 39,270 (94.4) 38,241 (91.9)
BMI (%)  < 0.001
 Health weight 61,871 (37.2) 16,472 (39.6) 16,114 (38.7) 15,205 (36.6) 14,080 (33.8)
 Underweight 908 (0.5) 236 (0.6) 247 (0.6) 194 (0.5) 231 (0.6)
 Overweight 69,587 (41.8) 17,196 (41.3) 17,443 (41.9) 17,551 (42.2) 17,397 (41.8)
 Obesity 34,011 (20.4) 7683 (18.5) 7803 (18.8) 8637 (20.8) 9888 (23.8)
Diabetes (%) 6847 (4.1) 1742 (4.2) 1570 (3.8) 1671 (4.0) 1864 (4.5)  < 0.001
Blood pressure status (%)  < 0.001
 Normal 27,949 (16.8) 6415 (15.4) 6873 (16.5) 6964 (16.7) 7697 (18.5)
 Elevated 22,181 (13.3) 5527 (13.3) 5671 (13.6) 5485 (13.2) 5498 (13.2)
 Hypertension stage 1 45,944 (27.6) 11,271 (27.1) 11,392 (27.4) 11,664 (28.0) 11,617 (27.9)
 Hypertension stage 2 70,303 (42.3) 18,374 (44.2) 17,671 (42.5) 17,474 (42.0) 16,784 (40.4)
Achieve the recommended physical activity level (%) 136,169 (81.8) 35,905 (86.3) 34,399 (82.7) 33,445 (80.4) 32,420 (77.9)  < 0.001
Energy, kcal/day (mean ± SD) 2075.06 ± 606.00 2477.95 ± 666.68 2189.28 ± 498.79 1977.78 ± 448.94 1655.27 ± 461.69  < 0.001
Family history of dementia (%) 21,800 (13.1) 5782 (13.9) 5603 (13.5) 5369 (12.9) 5046 (12.1)  < 0.001

TDI Townsend deprivation index, BMI Body mass index, SD Standard deviation

aQuartiles of dietary inflammation index. The cutoff points of the quartiles are − 1.799, − 0.395, 0.985

bAnalysis of variance or χ2 test where appropriate