Table 1.
Tumor characteristics and perioperative outcomes of MIBC patients undergoing radical cystectomy with a neobladder via the Studer and Y-pouch techniques
| Characteristics | Studer neobladder (n = 54) | Y-pouch neobladder (n = 36) | Total (n = 90) | P value |
|---|---|---|---|---|
| Age, mean (± SD) | 62.5 (± 10.7) | 62.7 (± 11.9) | 62.6 (± 11) | 0.957 |
| Gender, n (%) | ||||
| Male | 54 (100) | 28 (77.8) | 82 (91.1) | 0.021 |
| Female | 0 (0) | 8 (22.2) | 8 (8.9) | |
| Presentation | ||||
| Gross hematuria | 46 (85.2) | 36 (100) | 82 (91.1) | 0.406 |
| Microscopic hematuria | 4 (7.4) | 0 (0) | 4 (4.4) | |
| No hematuria | 4 (7.4) | 0 (0) | 4 (4.4) | |
| Time to radical cystectomy (days) | ||||
| Median (IQR) | 53 (18.5, 78) | 69 (63.2, 109.5) | 65 (42, 92) | 0.05 |
| pT stage, n (%) | ||||
| 2 | 40 (74) | 28 (77.8) | 68 (75.5) | 0.199 |
| 3 | 12 (22.2) | 2 (5.6) | 14 (15.6) | |
| 4 | 2 (3.7) | 6 (16.7) | 8 (8.9) | |
| pN stage, n (%) | ||||
| 0 | 48 (88.9) | 32 (88.9) | 80 (88.9) | 0.573 |
| 1 | 6 (11.1) | 2 (5.6) | 8 (8.9) | |
| 2 | 0 (0) | 2 (5.6) | 2 (2.2) | |
| Grading | ||||
| Low grade | 2 (3.7) | 0 (0) | 2 (2.2) | |
| High grade | 52 (96.3) | 36 (100) | 88 (97.8) | |
| BMI | ||||
| Mean (± SD) | 23.2 (± 2.8) | 22.4 (± 2.7) | 22.9 (± 2.8) | 0.398 |
| Baseline Cr (mg/dL) | 1.02 (± 0.6) | 1.00 (± 0.7) | 1.01 (± 0.6) | 0.23 |
| Operative time | ||||
| Median (IQR) | 290 (242.5, 350) | 300 (271.2, 335) | 290 (255, 340) | 0.826 |
| Cystectomy time | ||||
| Median (IQR) | 140 (120, 150) | 130 (120, 157.5) | 140 (120, 150) | 0.797 |
| Neobladder time | ||||
| Median (IQR) | 150 (132.5, 200) | 155 (150, 185) | 155 (145, 200) | 0.78 |
| Blood loss (mL) | ||||
| Median (IQR) | 1300 (1000, 1650) | 1000 (800, 2000) | 1200(1000,1700) | 0.149 |
| Postoperative chemotherapy | 0.166 | |||
| No | 8 (14.8) | 12 (33.3) | 20 (22.2) | |
| Yes | 46 (85.2) | 24 (66.7) | 70 (77.8) | |
| Clean intermittent catheterization | 0.064 | |||
| Yes | 16 (29.6) | 2 (5.6) | 18 (20) | |
| No | 38 (70.4) | 34 (94.4) | 72 (80) | |
| Cystostomy | < 0.001 | |||
| No | 0 (0) | 34 (94.4) | 34 (37.8) | |
| Yes | 54 (100) | 2 (5.6) | 56 (62.2) | |
| Catheterization days | < 0.001 | |||
| Median (IQR) | 21 (21, 21) | 13.5 (10.2, 14) | 21 (14, 21) | |
IQR interquartile range, BMI body mass index