Table 3.
In vitro Susceptibilities of Fungal Isolates to Eight Antifungal Agents
| Antifungal Agents | AND | MCF | CAS | 5-FC | VRC | ITR | FLC | AMB | POS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
| Candida albicans (n=266) | ||||||||||||||||||
| S/WT | 266 | 100.00 | 266 | 100.00 | 265 | 99.62 | 257 | 96.62 | 237 | 89.10 | 219 | 82.33 | 238 | 89.47 | 266 | 100.00 | 242 | 90.98 |
| I/SDD | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 1 | 0.38 | 24 | 9.02 | - | - | 16 | 6.02 | - | - | - | - |
| R/NWT | 0 | 0.00 | 0 | 0.00 | 1 | 0.38 | 8 | 3.00 | 5 | 1.88 | 47 | 17.67 | 12 | 4.51 | 0 | 0.00 | 24 | 9.02 |
| Candida glabrata (n=121) | ||||||||||||||||||
| S/WT | 117 | 100.00 | 116 | 95.87 | 116 | 95.87 | 120 | 99.17 | 93 | 76.86 | 120 | 99.17 | 0 | 0 | 121 | 100.00 | 101 | 83.47 |
| I/SDD | 2 | 1.65 | 2 | 1.65 | 4 | 3.31 | 0 | 0.00 | - | - | - | - | 110 | 90.91 | - | - | - | - |
| R/NWT | 2 | 1.65 | 3 | 2.48 | 1 | 0.82 | 1 | 0.83 | 28 | 23.14 | 1 | 0.83 | 11 | 9.09 | 0 | 0.00 | 20 | 16.53 |
| Candida tropicalis (n=103) | ||||||||||||||||||
| S/WT | 102 | 99.03 | 103 | 100.00 | 102 | 99.03 | 101 | 98.06 | 67 | 65.05 | 97 | 94.17 | 71 | 68.93 | 103 | 100.00 | 57 | 55.34 |
| I/SDD | 1 | 0.97 | 0 | 0.00 | 1 | 0.97 | 0 | 0.00 | 17 | 16.50 | - | - | 8 | 7.77 | - | - | - | - |
| R/NWT | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 2 | 1.94 | 19 | 18.45 | 6 | 5.83 | 24 | 23.30 | 0 | 0.00 | 46 | 44.66 |
| Candida parapsilosis (n=25) | ||||||||||||||||||
| S/WT | 25 | 100.00 | 24 | 96.00 | 25 | 100.00 | 25 | 100.00 | 25 | 100.00 | 25 | 100.00 | 21 | 84.00 | 25 | 100.00 | 25 | 100.00 |
| I/SDD | 0 | 0.00 | 1 | 4.00 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | - | - | 0 | 0.00 | - | - | - | - |
| R/NWT | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 4 | 16.00 | 0 | 0.00 | 0 | 0.00 |
Abbreviations: AND, Anidulafungin; MCF, Micafungin; CAS, Caspofungin; 5-FC, 5-Flucytosine; VRC, Voriconazole; ITR, Itraconazole; FLC, Fluconazole; AMB, Amphotericin B; POS, Posaconazole; S, sensitive; I, intermediate; R, drug resistant; SDD, dose-dependent sensitive; WT, wild-type; NWT, non-wild-type.