Table 4.
Known-Group Validity for the Domains of the Sinonasal Outcome Test (SNOT-22) Adjusted by Multiple Linear Regression
| Total Score | Nasal | Ear/Facial | |||||||
| Coef. | SE | p | Coef. | SE | p | Coef. | SE | p | |
| Age (per 10 years) | −2.9 | 1.1 | 0.007* | −1.3 | 0.4 | 0.001* | −0.7 | 0.2 | <0.001* |
| Gender (female vs male) | 7.4 | 2.5 | 0.003* | 1.8 | 0.9 | 0.055 | 0.9 | 0.5 | 0.071 |
| AJCC staging (late vs early) | 1.7 | 2.5 | 0.497 | 0.9 | 0.9 | 0.324 | −0.2 | 0.5 | 0.731 |
| Treatment regimen (CRT vs RT) | 2.0 | 5.3 | 0.699 | 1.3 | 2.0 | 0.515 | 0.4 | 1.0 | 0.724 |
| Recurrence (yes vs no) | 14.1 | 4.6 | 0.002* | 4.4 | 1.7 | 0.011* | 2.9 | 0.9 | 0.001* |
| Acquiring time after RT | |||||||||
| 6 < QAT ≤ 24 months | (REF) | (REF) | (REF) | ||||||
| 24 < QAT ≤ 60 months | 2.2 | 3.1 | 0.477 | 0.6 | 1.2 | 0.610 | −0.1 | 0.6 | 0.894 |
| QAT > 60 months | 8.6 | 3.1 | 0.006* | 4.1 | 1.2 | <0.001* | 1.6 | 0.6 | 0.011* |
| Sleep | Function | Emotion | |||||||
| Coef. | SE | p | Coef. | SE | p | Coef. | SE | p | |
| Age (per 10 years) | −0.2 | 0.3 | 0.543 | −0.4 | 0.2 | 0.044* | −0.2 | 0.2 | 0.213 |
| Gender (female vs male) | 2.7 | 0.8 | <0.001* | 1.0 | 0.5 | 0.042* | 1.0 | 0.4 | 0.020* |
| AJCC staging (late vs early) | −0.1 | 0.8 | 0.930 | 0.3 | 0.5 | 0.553 | 0.7 | 0.4 | 0.084 |
| Treatment regimen (CRT vs RT) | 0.6 | 1.7 | 0.709 | −0.7 | 1.0 | 0.480 | 0.5 | 0.9 | 0.577 |
| Recurrence (yes vs no) | 1.6 | 1.5 | 0.284 | 2.5 | 0.9 | 0.005* | 2.7 | 0.8 | <0.001* |
| Acquiring time after RT | |||||||||
| 6 < QAT ≤ 24 months | (REF) | (REF) | (REF) | ||||||
| 24 < QAT ≤ 60 months | 0.7 | 1.0 | 0.487 | 0.3 | 0.6 | 0.656 | 0.7 | 0.5 | 0.161 |
| QAT > 60 months | 1.1 | 1.0 | 0.299 | 1.0 | 0.6 | 0.113 | 0.9 | 0.5 | 0.085 |
Note: *p ≤ 0.05.
Abbreviations: AJCC, American Joint Committee on Cancer; Coef., Coefficient; CRT, chemoradiotherapy; SE, standard error; QAT, questionnaire acquiring time.