Figure 3.
Root mean square fluctuation (RMSF) analysis of CHMO DTNP. Results are plotted as the difference in RMSF between DTNP (with NADH bound) and WT (with NADH or NADPH bound, respectively). The control loop is found to have greater stability with DTNP:NADH, comparable to the native condition of WT:NADPH. The inactive pairing of WT:NADH exhibits high flexibility at the control loop.
