Table 1.

Selection Criteria for Cohorts at the Enrollment Study Visit

Cohort	MMQS*,†	Schirmer Test Without Anesthesia†	Sum of Worst 2 Symptom Scores on the Subject Ocular Symptom Questionnaire‡
Non-MGD	0 or 1§	≥7 mm/5 min	0 to 4 with neither symptom scored as >2
Mild-to-moderate MGD	2§	≥7 mm/5 min	0 to 4 with neither symptom scored as >2
Severe MGD	3	≥7 mm/5 min	≥4

MGD, meibomian gland dysfunction; MMQS, maximum meibum quality score.

Selection criteria from the latest protocol amendment are listed. The MMQS was graded by the investigator; higher scores indicate lower quality of the secretion.

^*Only six central glands in the lower lids were examined and graded.

^†MMQS and Schirmer test criteria must be met in the same eye (the study eye providing the meibum sample analyzed).

^‡Scored by the study participant.

^§No gland among the six central glands being graded may have a meibum quality score greater than the MMQS specified in the cohort designation.